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Generative artificial intelligence (AI) is becoming a common tool for students, making it important to teach them how to use it responsibly. We developed a group project for an undergraduate microbiology course in which students use AI to create an infectious disease case study. After researching an assigned infectious disease, each group designs a prompt to generate a realistic clinical case. Students then compare the AI-generated case with information from textbooks and other reliable scientific sources to verify the accuracy of the organism's biology, disease process, diagnosis, laboratory findings, and treatment. They revise the case as needed before presenting it to the class. During the presentation, students explain how they developed their case, discuss the challenges and benefits of using AI, and reflect on what they learned. This activity encourages students to apply microbiology concepts, think critically about AI-generated information, and develop skills in collaboration and clinical reasoning.
